abstract：:Chronic neck and shoulder pain (CNSP) is a common musculoskeletal disorder in adults, which is linked to hypersensitivity to noxious stimuli. The hormone oxytocin has been implicated as a potential therapeutic for the management of chronic pain disorders, and has been suggested to have sex-specific effects on the sali...

journal_title：Psychoneuroendocrinology

authors： Tracy LM,Labuschagne I,Georgiou-Karistianis N,Gibson SJ,Giummarra MJ

更新日期：2017-09-01 00:00:00

abstract：:Etifoxine is indicated in humans for treating anxiety. In rodents, besides its anxiolytic-like properties, it has recently shown neuroprotective and neuroregenerative activities. It acts by enhancing GABAA receptor function and by stimulating acute steroid biosynthesis via the activation of the 18-kDa translocator pro...

journal_title：Psychoneuroendocrinology

authors： Liere P,Pianos A,Oudinet JP,Schumacher M,Akwa Y

更新日期：2017-09-01 00:00:00

abstract：:Type 2 diabetes (T2D) has been associated with cognitive decline, dementia and Alzheimer's disease (AD). Remarkably, the pathophysiological mechanisms behind this are still mostly unknown. Cognition and memory formation are associated with gamma oscillations in hippocampal neuronal networks and fast-spiking, parvalbum...

journal_title：Psychoneuroendocrinology

authors： Lietzau G,Darsalia V,Pintana H,Östenson CG,Nyström T,Fisahn A,Patrone C

更新日期：2017-08-01 00:00:00

abstract：:Early life adversity (ELA) is associated with a higher risk for diseases in adulthood. Although the pathophysiological effects of ELA are varied, there may be a unifying role for the immune system in all of the long-term pathologies such as chronic inflammatory disorders (autoimmune diseases, allergy, and asthma). Rec...

journal_title：Psychoneuroendocrinology

authors： Elwenspoek MMC,Kuehn A,Muller CP,Turner JD

更新日期：2017-08-01 00:00:00

abstract：:Hypersexual Disorder (HD) defined as non-paraphilic sexual desire disorder with components of compulsivity, impulsivity and behavioral addiction, and proposed as a diagnosis in the DSM 5, shares some overlapping features with substance use disorder including common neurotransmitter systems and dysregulated hypothalami...

journal_title：Psychoneuroendocrinology

authors： Jokinen J,Boström AE,Chatzittofis A,Ciuculete DM,Öberg KG,Flanagan JN,Arver S,Schiöth HB

更新日期：2017-06-01 00:00:00

abstract：:Based on a large population of 1113 men aged 30-60 at baseline (mean: 44.1 years, standard deviation: 10.5), we investigated whether intra-individual changes in testosterone (T) and related reproductive hormones during a ten year period were dependent of marital status at baseline and follow-up. The studied men were p...

journal_title：Psychoneuroendocrinology

authors： Holmboe SA,Priskorn L,Jørgensen N,Skakkebaek NE,Linneberg A,Juul A,Andersson AM

更新日期：2017-06-01 00:00:00

abstract：:The present study examined how the interplay of partners' attachment styles influences cortisol response, actual closeness, and desired closeness during friendship initiation. Participants provided salivary cortisol samples at four timepoints throughout either a high or low closeness task that facilitated high or low ...

journal_title：Psychoneuroendocrinology

authors： Ketay S,Beck LA

更新日期：2017-06-01 00:00:00

abstract：:Current evidence is mixed on the role of progesterone and its metabolites in perinatal mood and anxiety disorders. We measured second and third trimester (T2 and T3) progesterone (PROG) and allopregnanolone (ALLO) levels by ELISA and postpartum depression (PPD) by clinician interview (DSM-IV criteria) in 60 pregnant w...

journal_title：Psychoneuroendocrinology

authors： Osborne LM,Gispen F,Sanyal A,Yenokyan G,Meilman S,Payne JL

更新日期：2017-05-01 00:00:00

abstract：:Childhood maltreatment leads to a host of negative physical and mental health outcomes, with cortisol dysregulation implicated as a possible mechanism. Given inconsistencies across in the literature regarding the direction and magnitude of the association between maltreatment and diurnal cortisol regulation, the curre...

journal_title：Psychoneuroendocrinology

authors： Bernard K,Frost A,Bennett CB,Lindhiem O

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Currently, no valid measures inform treatment selection for depressed patients. Whether C-reactive protein (CRP) in particular and two other acute phase reactants (inflammatory markers) could differentiate between patients responding to either of two treatments with different mechanisms of action was assessed...

journal_title：Psychoneuroendocrinology

authors： Jha MK,Minhajuddin A,Gadad BS,Greer T,Grannemann B,Soyombo A,Mayes TL,Rush AJ,Trivedi MH

更新日期：2017-04-01 00:00:00

abstract：:Married people tend to be healthier than both the previously (bereaved, divorced, and separated) and never married, but the mechanisms through which this occurs remain unclear. To this end, research has increasingly focused on how psychological stress experienced by unmarried versus married individuals may differentia...

journal_title：Psychoneuroendocrinology

authors： Chin B,Murphy MLM,Janicki-Deverts D,Cohen S

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Posttraumatic stress symptoms (PTSS) are commonly associated with impairments in extinguishing fear to signals previously associated with danger, and also with inhibiting fear to safety signals. Previous studies indicate that PTSS are associated with low cortisol activity, and cortisol is shown to facilitate ...

journal_title：Psychoneuroendocrinology

authors： Zuj DV,Palmer MA,Malhi GS,Bryant RA,Felmingham KL

更新日期：2017-04-01 00:00:00

abstract：:Why some individuals seek social engagement while others shy away has profound implications for normal and pathological human behavior. Evidence suggests that oxytocin (OT), the paramount human social hormone, and CD38 that governs OT release, contribute to individual differences in social skills from intense social i...

journal_title：Psychoneuroendocrinology

authors： Chong A,Malavasi F,Israel S,Khor CC,Yap VB,Monakhov M,Chew SH,Lai PS,Ebstein RP

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The crucial role of the hypothalamic-pituitary-adrenal axis (HPA) in stress-related homeostasis suggests dysregulated HPA involvement in the pathogenesis of post-traumatic stress disorder (PTSD), yet most studies examining linkages between HPA axis measures and PTSD have yielded null findings. One untested e...

journal_title：Psychoneuroendocrinology

authors： Josephs RA,Cobb AR,Lancaster CL,Lee HJ,Telch MJ

更新日期：2017-04-01 00:00:00

abstract：:Previous research has found an association between a smaller cerebellar volume and higher levels of neuroticism. The steroid hormone testosterone reduces stress responses and the susceptibility to negative mood. Together with in vitro studies showing a positive effect of testosterone on cerebellar gray matter volumes,...

journal_title：Psychoneuroendocrinology

authors： Schutter DJLG,Meuwese R,Bos MGN,Crone EA,Peper JS

更新日期：2017-04-01 00:00:00

abstract：:Previous work suggests that estradiol regulates the expression of hippocampal parvalbumin as well as hippocampus-dependent spatial memory in mice. Parvalbumin interneurons generate neuronal oscillatory activity in the gamma frequency range (30-80Hz) and gamma oscillations are closely linked with higher cognitive funct...

journal_title：Psychoneuroendocrinology

authors： Schroeder A,Hudson M,Du X,Wu YWC,Nakamura J,van den Buuse M,Jones NC,Hill RA

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:A proportion of patients with panic disorder (PD) fail to show a remission after psychotherapy. Biological correlates of psychotherapy non-response have rarely been described in the literature. The aim of the present study was to research the relationship between the cortisol stress response and the psychoth...

journal_title：Psychoneuroendocrinology

authors： Wichmann S,Kirschbaum C,Lorenz T,Petrowski K

更新日期：2017-03-01 00:00:00

abstract：:Brief physical exercise enhances memories for neutral events, and modulates fear learning in animals. Exercise-induced arousal induces the release of brain-derived neurotrophic factor (BDNF), which may moderate memory-enhancing effects. This study investigated the effect of exercise, and the extent to which the BDNF v...

journal_title：Psychoneuroendocrinology

authors： Keyan D,Bryant RA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Hair cortisol concentration (HCC) has been suggested as a promising marker for chronic stress. However, studies investigating the influence of hair dyeing and hair washing frequency on HCC have shown inconsistent results. OBJECTIVE:To examine associations between HCC and hair dyeing status or weekly hair wa...

journal_title：Psychoneuroendocrinology

authors： Kristensen SK,Larsen SC,Olsen NJ,Fahrenkrug J,Heitmann BL

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Brain-derived neurotrophic factor (BDNF) supports neurogenesis, angiogenesis, and promotes the survival of various cell types in the brain and the coronary system. Moreover, BDNF is associated with both coronary heart disease (CHD) and depression. The current study aims to investigate whether serum BDNF level...

journal_title：Psychoneuroendocrinology

authors： Kuhlmann SL,Tschorn M,Arolt V,Beer K,Brandt J,Grosse L,Haverkamp W,Müller-Nordhorn J,Rieckmann N,Waltenberger J,Warnke K,Hellweg R,Ströhle A

更新日期：2017-03-01 00:00:00

abstract：:Cortisol, the primary glucocorticoid (GC) in humans, influences neuronal excitability and plasticity by acting on mineralocorticoid and glucocorticoid receptors. Cellular studies demonstrated that elevated GC levels affect neuronal plasticity, for example through a reduction of hippocampal long-term potentiation (LTP)...

journal_title：Psychoneuroendocrinology

authors： Dinse HR,Kattenstroth JC,Lenz M,Tegenthoff M,Wolf OT

更新日期：2017-03-01 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) is a key component of the neuroendocrine response to stress. In animal models, CRH has been shown to modulate dopamine release, and this interaction is believed to contribute to stress-induced relapse in neuropsychiatric disorders. Here we investigated whether CRH administration i...

journal_title：Psychoneuroendocrinology

authors： Payer D,Williams B,Mansouri E,Stevanovski S,Nakajima S,Le Foll B,Kish S,Houle S,Mizrahi R,George SR,George TP,Boileau I

更新日期：2017-02-01 00:00:00

abstract：:Police officers encounter unpredictable, evolving, and escalating stressful demands in their work. Utilizing the Spielberger Police Stress Survey (60-item instrument for assessing specific conditions or events considered to be stressors in police work), the present study examined the association of the top five highly...

journal_title：Psychoneuroendocrinology

authors： Violanti JM,Fekedulegn D,Andrew ME,Hartley TA,Charles LE,Miller DB,Burchfiel CM

更新日期：2017-01-01 00:00:00

abstract：:Evidence suggests the putative human pheromone Δ4,16-androstadien-3-one (androstadienone), a natural component of human sweat, increases attention to emotional information when passively inhaled, even in minute amounts. However, the neural mechanisms underlying androstadienone's impact on the perception of emotional s...

journal_title：Psychoneuroendocrinology

authors： Hummer TA,Phan KL,Kern DW,McClintock MK

更新日期：2017-01-01 00:00:00

abstract：:Frontal EEG asymmetry is thought to reflect variations in affective style, such that greater relative right frontal activity at rest predicts enhanced emotional responding to threatening or negative stimuli, and risk of depression and anxiety disorders. A diathesis-stress model has been proposed to explain how this ne...

journal_title：Psychoneuroendocrinology

authors： Hostinar CE,Davidson RJ,Graham EK,Mroczek DK,Lachman ME,Seeman TE,van Reekum CM,Miller GE

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Cognitive behavioral stress management (CBSM) is an empirically-validated group-based psychosocial intervention. CBSM is related to decreased self-reported indicators of psychological adversity during breast cancer treatment and greater disease-free survival (DFS) vs. a control condition. This study examined re...

journal_title：Psychoneuroendocrinology

authors： Antoni MH,Bouchard LC,Jacobs JM,Lechner SC,Jutagir DR,Gudenkauf LM,Carver CS,Lutgendorf S,Cole SW,Lippman M,Blomberg BB

更新日期：2016-12-01 00:00:00

abstract：:Animal models and human studies using paradigms designed to stimulate endogenous oxytocin release suggest a stress-buffering role of oxytocin. We here examined the involvement of stress-induced peripheral oxytocin secretion in reactivity and recovery phases of the human psychosocial stress response. Healthy male and f...

journal_title：Psychoneuroendocrinology

authors： Engert V,Koester AM,Riepenhausen A,Singer T

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:No simple way to augment fear extinction has been established. Cortisol has shown to enhance memory extinction and preliminary evidence suggest that extinction learning maybe more successful in the morning when cortisol is high. The aim was to determine whether exposure sessions conducted earlier in the day a...

journal_title：Psychoneuroendocrinology

authors： Meuret AE,Rosenfield D,Bhaskara L,Auchus R,Liberzon I,Ritz T,Abelson JL

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Whereas childhood adversity (CA) and the hypothalamus-pituitary-adrenal (HPA) axis have been suggested to play a major role in the etiology of non-suicidal self-injury (NSSI), no study has thus far investigated both its associations and interactions with adolescent NSSI. METHOD:We investigated CA (antipathy...

journal_title：Psychoneuroendocrinology

authors： Reichl C,Heyer A,Brunner R,Parzer P,Völker JM,Resch F,Kaess M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Stress evokes lipolytic release of free fatty acid (FFA) and low-grade inflammation in visceral adipose tissue, mediated by increased adipokine secretion, and contributes to glucose metabolism disorder and prothrombotic state. We tested the hypothesis that alogliptin, a dipeptidyl peptidase-4 inhibitor, can ...

journal_title：Psychoneuroendocrinology

authors： Yisireyili M,Takeshita K,Hayashi M,Wu H,Uchida Y,Yamamoto K,Kikuchi R,Hao CN,Nakayama T,Cheng XW,Matsushita T,Nakamura S,Murohara T

更新日期：2016-11-01 00:00:00

abstract：:Stress and inflammation are both important risk factors for coronary artery disease (CAD). However, the susceptibility to stress-induced inflammation and its determinants have been little explored in patients with CAD. Here, our aim was to study the stress-induced inflammatory response, more precisely the early releas...

journal_title：Psychoneuroendocrinology

authors： Lundberg AK,Jönsson S,Stenmark J,Kristenson M,Jonasson L

更新日期：2016-11-01 00:00:00

abstract：:Hair cortisol concentrations (HCC) have been suggested to reflect long-term integrated cortisol levels, but most evidence of associations with co-variates is from small samples of healthy volunteers. The objective of this study was to describe the collection of hair samples in a large cohort study and report associati...

journal_title：Psychoneuroendocrinology

authors： Abell JG,Stalder T,Ferrie JE,Shipley MJ,Kirschbaum C,Kivimäki M,Kumari M

更新日期：2016-11-01 00:00:00

abstract：:Children with antisocial and aggressive behaviors have been found to show abnormal neurobiological responses to stress, specifically impaired cortisol stress reactivity. The role of individual characteristics, such as comorbid anxiety, in the stress response is far less studied. Furthermore, this study extended previo...

journal_title：Psychoneuroendocrinology

authors： Schoorl J,Rijn SV,Wied M,van Goozen S,Swaab H

更新日期：2016-11-01 00:00:00

abstract：:In Autism Spectrum Disorders (ASD), a bias to a higher incidence in boys than in girls has been reported. With the aim to identify biological mechanisms acting in female animals that could underlie this bias, we used an extensively validated mouse model of ASD: the prenatal exposure to valproic acid (VPA). We found po...

journal_title：Psychoneuroendocrinology

authors： Kazlauskas N,Campolongo M,Lucchina L,Zappala C,Depino AM

更新日期：2016-10-01 00:00:00

abstract：:The bed nucleus of the stria terminalis (BNST) plays a critical role in fear and anxiety. The BNST is important for contextual fear learning, but the mechanisms regulating this function remain unclear. One candidate mechanism is corticotropin-releasing-factor (CRF) acting at CRF type 1 receptors (CRFr1s). Yet, there h...

journal_title：Psychoneuroendocrinology

authors： Asok A,Schulkin J,Rosen JB

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Bipolar disorder (BD) and schizophrenia (SCZ) are psychiatric disorders with shared and distinct clinical and genetic features. In both disorders, stress increases the risk for onset or relapse and dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis has been reported. The latter is frequently in...

journal_title：Psychoneuroendocrinology

authors： Streit F,Memic A,Hasandedić L,Rietschel L,Frank J,Lang M,Witt SH,Forstner AJ,Degenhardt F,Wüst S,Nöthen MM,Kirschbaum C,Strohmaier J,Oruc L,Rietschel M

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:African Americans (AA) experience higher levels of stress related to living in racially segregated and poor neighborhoods. However, little is known about the associations between perceived neighborhood environments and cellular aging among adult AA. This study examined whether perceived neighborhood environm...

journal_title：Psychoneuroendocrinology

authors： Gebreab SY,Riestra P,Gaye A,Khan RJ,Xu R,Davis AR,Quarells RC,Davis SK,Gibbons GH

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Chronic psychosocial stress is a crucial risk factor in the development of many diseases including obesity. Neuropeptide Y (NPY), distributed throughout the peripheral and central nervous system, is believed to pay a role in the pathophysiologic relationship between stress and obesity. Although several anima...

journal_title：Psychoneuroendocrinology

authors： Kim HJ,Min KB,Min JY

更新日期：2016-07-01 00:00:00

abstract：:The peptide hormone oxytocin (OT) plays an important role in social behaviors, including social bond formation. In different contexts, however, OT is also associated with aggression, social selectivity, and reduced affiliation. Female meadow voles form social preferences for familiar same-sex peers under short, winter...

journal_title：Psychoneuroendocrinology

authors： Anacker AM,Christensen JD,LaFlamme EM,Grunberg DM,Beery AK

更新日期：2016-06-01 00:00:00

abstract：:The endocannabinoid system has been implicated in the regulation of the stress response, fear memory formation, and inflammatory processes. Posttraumatic stress disorder (PTSD) can result from exposure to extreme stress and is characterized by strong, associative memories for the traumatic events experienced. Furtherm...

journal_title：Psychoneuroendocrinology

authors： Wilker S,Pfeiffer A,Elbert T,Ovuga E,Karabatsiakis A,Krumbholz A,Thieme D,Schelling G,Kolassa IT

更新日期：2016-05-01 00:00:00